Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12031024 | 0.83 | CES1 (0.39) | CYP19A1ANPEPCES1DNMT1ALDH1A1 | |
| SCHEMBL1825039 | 0.79 | ACHE (0.49) | CYP19A1ANPEPCES1DNMT1 | |
| SCHEMBL9325902 | 0.72 | CES1 (0.38) | CYP19A1ANPEPCES1DNMT1ALDH1A1 | |
| SCHEMBL8653085 | 0.72 | CYP19A1 (0.41) | CYP19A1ANPEPDNMT1ALDH1A1KDM4E | |
| SCHEMBL30286791 | 0.70 | CYP19A1 (0.38) | CYP19A1ANPEPDNMT1 | |
| SCHEMBL9174741 | 0.70 | CYP19A1 (0.38) | CYP19A1ANPEPDNMT1 | |
| SCHEMBL6987200 | 0.68 | DNMT1 (0.46) | ANPEPCES1DNMT1ALDH1A1KDM4E | |
| SCHEMBL8552212 | 0.68 | CES1 (0.34) | CES1 | |
| SCHEMBL6759607 | 0.67 | DNMT1 (0.44) | ANPEPCES1DNMT1ALDH1A1KDM4E | |
| SCHEMBL30617063 | 0.67 | DNMT1 (0.44) | ANPEPCES1DNMT1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078068-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED 2-HALO-BENZINDENE COMPOUNDS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-05-03 | — | — | WO | disclosed |