Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113277 | 0.72 | CYP19A1 (0.43) | CES1CYP19A1DNMT1ALDH1A1LMNA | |
| SCHEMBL87603 | 0.71 | DNMT1 (0.42) | CES1CYP19A1DNMT1ALDH1A1MEN1 | |
| SCHEMBL12031024 | 0.70 | CES1 (0.39) | CES1CYP19A1DNMT1ALDH1A1LMNA | |
| SCHEMBL9094355 | 0.69 | S100A4 (0.35) | ALDH1A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL86218 | 0.69 | ALDH1A1 (0.50) | CES1DNMT1ALDH1A1MEN1KMT2A | |
| SCHEMBL7912378 | 0.67 | MAPT (0.39) | CES1CYP19A1DNMT1ALDH1A1MEN1 | |
| SCHEMBL13889246 | 0.65 | ALDH1A1 (0.40) | CES1DNMT1ALDH1A1MEN1KMT2A | |
| SCHEMBL17875144 | 0.65 | ALDH1A1 (0.40) | CES1DNMT1ALDH1A1MEN1KMT2A | |
| SCHEMBL18059289 | 0.64 | ANPEP (0.41) | ALDH1A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL18533303 | 0.64 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347012-A | Naphthothiopyranone derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0535232-A1 | NAPHTHOTHIOPYRANONE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |