Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011332 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KCNA3KCNA5MAPTSMN1; SMN2 | |
| SCHEMBL2875594 | 0.84 | KCNA5 (0.42) | ALDH1A1KCNA3KCNA5MAPTSMN1; SMN2 | |
| SCHEMBL2889248 | 0.81 | L3MBTL1 (0.34) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2883991 | 0.76 | KCNA5 (0.42) | ALDH1A1KCNA3KCNA5MAPTSMN1; SMN2 | |
| SCHEMBL2011330 | 0.74 | KCNA5 (0.38) | ALDH1A1KCNA3KCNA5MAPTSMN1; SMN2 | |
| SCHEMBL4941253 | 0.73 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3599146 | 0.73 | KCNE1 (0.40) | ALDH1A1KCNA5CYP3A4 | |
| SCHEMBL3599142 | 0.73 | KCNE1 (0.40) | ALDH1A1KCNA5CYP3A4 | |
| SCHEMBL12580760 | 0.72 | ABCB1 (0.42) | KCNA5CYP3A4 | |
| SCHEMBL2891901 | 0.71 | NPC1 (0.41) | ALDH1A1KCNA3KCNA5MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964623-B2 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2011-06-21 | — | — | US | disclosed |