Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB4 | Q16877 | 5/20 | 0.62 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787754 | 0.77 | PFKFB4 (1.00) | PFKFB4PFKFB3POLBTCF4CTNNB1 | |
| SCHEMBL15619156 | 0.70 | PFKFB4 (0.55) | PFKFB4PFKFB3MAPTALDH1A1KMT2A | |
| SCHEMBL30444044 | 0.70 | RAB9A (0.56) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL787993 | 0.65 | PFKFB4 (1.00) | PFKFB4PFKFB3ALDH1A1KMT2ANPC1 | |
| SCHEMBL5928273 | 0.64 | KMT2A (0.61) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL31370875 | 0.64 | PFKFB3 (0.46) | PFKFB4PFKFB3MAPTALDH1A1KMT2A | |
| SCHEMBL16386082 | 0.64 | TCF4 (0.52) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL788343 | 0.64 | PFKFB4 (1.00) | PFKFB4PFKFB3POLBTCF4CTNNB1 | |
| SCHEMBL3689081 | 0.63 | ALDH1A1 (0.53) | PFKFB4PFKFB3MAPTALDH1A1KMT2A | |
| SCHEMBL3190591 | 0.63 | PFKFB3 (0.46) | PFKFB4PFKFB3MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |