Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.62 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.62 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.62 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268478 | 1.00 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL13301072 | 0.91 | CYP3A4 (0.61) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL8104629 | 0.90 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL3224386 | 0.90 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL13301071 | 0.90 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Efinaconazole SCHEMBL8376515 | 0.89 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Efinaconazole SCHEMBL8375862 | 0.89 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Efinaconazole SCHEMBL20017139 | 0.89 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL20913723 | 0.89 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Efinaconazole SCHEMBL18289604 | 0.89 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10245257-B2 | Anti-infective methods, compositions, and devices | DOW PHARMACEUTICAL SCIENCES, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180118714-A1 | PROCESS FOR THE PREPARATION OF EFINACONAZOLE | LUPIN LIMITED (IN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118714-A1 | PROCESS FOR THE PREPARATION OF EFINACONAZOLE | CYP3A4, ERG28, CYP4Z1 | CYP3A4 1/4885CYP2C9 47/4885CYP2C19 31/4885 |
| US-10245257-B2 | Anti-infective methods, compositions, and devices | ETF1, POLR1C, PIK3C3 | CYP3A4 1575/4885CYP2C9 960/4885CYP2C19 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.