Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 11/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628187 | 0.84 | ALDH1A1 (0.53) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2018212 | 0.84 | ALDH1A1 (0.53) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2016436 | 0.84 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2016241 | 0.84 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL12628299 | 0.84 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL12628522 | 0.83 | ALDH1A1 (0.51) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2013487 | 0.81 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2AEPHX2GHSR | |
| SCHEMBL12628295 | 0.81 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2AEPHX2GHSR | |
| SCHEMBL2016541 | 0.79 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AKDM1AEPHX2 | |
| SCHEMBL12629087 | 0.79 | ALDH1A1 (0.65) | ALDH1A1RAB9AKMT2APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |