Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | TLR2 | O60603 | 12/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 11/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628187 | 0.85 | ALDH1A1 (0.53) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2018212 | 0.85 | ALDH1A1 (0.53) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2016241 | 0.82 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL2016436 | 0.82 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL12628299 | 0.82 | ALDH1A1 (0.52) | ALDH1A1RAB9AKMT2AEPHX2GAA | |
| SCHEMBL12629087 | 0.81 | ALDH1A1 (0.65) | ALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2011747 | 0.81 | ALDH1A1 (0.65) | ALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL12628172 | 0.81 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2AEPHX2 | |
| SCHEMBL2013828 | 0.81 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL12629075 | 0.81 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |