SCHEMBL2011584

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2004188	0.95	HTR3A (0.46)	HTR3AADRB1HTR3EHTR3BHTR3D
	SCHEMBL3063833	0.86	CNR1 (0.43)	HTR3AADRB1HTR6HTR2BCETP
	SCHEMBL1022439	0.85	ADRB1 (0.51)	HTR3AADRB1HTR6HTR1AHTR1B
	SCHEMBL3059952	0.85	CNR1 (0.48)	HTR3AADRB1HTR6HTR1AHTR1B
	SCHEMBL2005763	0.84	HTR6 (0.40)	HTR3AADRB1HTR3EHTR3BHTR3D
	SCHEMBL2002640	0.83	CETP (0.59)	HTR3AADRB1HTR3EHTR3BHTR3D
	SCHEMBL1021015	0.83	HTR2B (0.44)	HTR3AHTR6HTR1AHTR7HTR2B
	SCHEMBL3059021	0.83	CNR1 (0.45)	HTR3AADRB1HTR6HTR1AHTR1B
	SCHEMBL2007325	0.82	TAAR1 (0.51)	HTR3AADRB1HTR3EHTR3BHTR3D
	SCHEMBL2008345	0.82	ADRB1 (0.47)	HTR3AADRB1HTR6HTR1AHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.