Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | RORB | Q92753 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116772 | 0.83 | RORC (0.39) | RORARORCRORBKAT8CNR2 | |
| SCHEMBL25919850 | 0.78 | RORA (0.39) | RORARORCRORBPGRGPR3 | |
| SCHEMBL25920074 | 0.77 | RORA (0.42) | RORARORCRORBPGRGPR3 | |
| SCHEMBL18707415 | 0.77 | RORA (0.42) | RORARORCRORBPGRCNR2 | |
| SCHEMBL13323477 | 0.75 | RORA (0.45) | RORARORCRORBPGRNPC1 | |
| SCHEMBL23372135 | 0.75 | RORA (0.54) | RORARORCRORBPGRGPR3 | |
| SCHEMBL12628219 | 0.75 | FAAH (0.47) | RORARORCRORBPGRTP53 | |
| SCHEMBL25919860 | 0.75 | RORA (0.38) | RORARORCRORBPGRPOLB | |
| SCHEMBL18707365 | 0.75 | RORA (0.40) | RORARORCRORBPGR | |
| SCHEMBL4546856 | 0.74 | RORA (0.49) | RORARORCRORBTP53GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |