Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380368 | 0.87 | USP14 (0.36) | RORCPTGER4 | |
| SCHEMBL20116771 | 0.86 | RORC (0.32) | RORC | |
| SCHEMBL20115893 | 0.83 | RORA (0.41) | RORCRORARORBKAT8CNR2 | |
| SCHEMBL17115468 | 0.81 | RORC (0.42) | RORCRORARORBTSHRHSD17B10 | |
| SCHEMBL17115459 | 0.81 | RORC (0.42) | RORCRORARORBTSHRHSD17B10 | |
| SCHEMBL20116769 | 0.81 | RORC (0.36) | RORCPTGER4 | |
| SCHEMBL20116770 | 0.80 | USP14 (0.35) | RORC | |
| SCHEMBL17115483 | 0.79 | CYP1A2 (0.42) | RORCRORARORBTSHRHSD17B10 | |
| SCHEMBL17115487 | 0.79 | CYP1A2 (0.42) | RORCRORARORBTSHRHSD17B10 | |
| SCHEMBL17115382 | 0.78 | TSHR (0.42) | RORCRORARORBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |