SCHEMBL2011615

SCHEMBL2011615

Fc1ccc(C(Br)=CBr)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
PTPN1 P18031 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
TNFRSF1A P19438 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 1/20 0.36
LTA4H P09960 1/20 0.35
PTGS1 P23219 1/20 0.35
FBP1 P09467 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
CTSL P07711 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273189 1.00 CES2 (0.44) CES2CES1PTPN1CA1CA2
SCHEMBL16634441 0.77 MAPT (0.44) PTPN1CA1CA2RAB9ANPC1
SCHEMBL28273257 0.77 CES2 (0.46) CES2CES1CA1CA2RAB9A
SCHEMBL28249940 0.77 CES2 (0.46) CES2CES1PTPN1CA1CA2
SCHEMBL28273256 0.77 CES2 (0.46) CES2CES1CA1CA2RAB9A
SCHEMBL16795703 0.75 CES2 (0.44) CES2CES1CA1CA2MAPT
SCHEMBL28274783 0.75 ALDH1A1 (0.44) CES2CES1MAPTSMN1; SMN2
SCHEMBL28858460 0.75 CES2 (0.44) CES2CES1CA1CA2MAPT
SCHEMBL28274784 0.75 ALDH1A1 (0.44) CES2CES1MAPTSMN1; SMN2
SCHEMBL16795702 0.75 CES2 (0.44) CES2CES1CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197046-B Halogenation method of unsaturated hydrocarbon 华南理工大学 2023-12-15 CN disclosed
CN-115197046-A Halogenation method of unsaturated hydrocarbon 华南理工大学 2022-10-18 CN disclosed
CN-109265325-B 1, 2-dibromo olefin compound and preparation method and application thereof 广东工业大学 2021-12-17 CN disclosed
CN-109265325-A A kind of bis- bromo alkenes compounds of 1,2- and its preparation method and application 广东工业大学 2019-01-25 CN disclosed
WO-2011066954-A1 π-CONJUGATED POLYMERS CONTAINING FLUOROARYLVINYLEDENE UNITS AND RELATIVE PREPARATION PROCESS ENI S.P.A. (IT) 2011-06-09 WO disclosed