Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634441 | 0.79 | MAPT (0.44) | CA1CA2ALOX15RECQLCYP1A2 | |
| SCHEMBL28858460 | 0.77 | CES2 (0.44) | CES2CES1GSK3BCA1CA2 | |
| SCHEMBL16795703 | 0.77 | CES2 (0.44) | CES2CES1GSK3BCA1CA2 | |
| SCHEMBL16795702 | 0.77 | CES2 (0.44) | CES2CES1GSK3BCA1CA2 | |
| SCHEMBL2011615 | 0.77 | CES2 (0.44) | CES2CES1CA1CA2CYP1A2 | |
| SCHEMBL5905848 | 0.76 | CES1 (0.39) | CES2CES1GSK3BCA1CA2 | |
| SCHEMBL5905850 | 0.76 | CES1 (0.39) | CES2CES1GSK3BCA1CA2 | |
| SCHEMBL28615013 | 0.73 | CES2 (0.46) | CES2CES1GSK3BCA1CA2 | |
| SCHEMBL28858522 | 0.73 | ALDH1A1 (0.52) | CYP2A6RAB9AALDH1A1 | |
| SCHEMBL28858528 | 0.73 | ALDH1A1 (0.52) | CYP2A6RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265325-B | 1, 2-dibromo olefin compound and preparation method and application thereof | 广东工业大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-109265325-A | A kind of bis- bromo alkenes compounds of 1,2- and its preparation method and application | 广东工业大学 | 2019-01-25 | — | — | CN | disclosed |