Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30506324 | 0.85 | TRPM8 (0.41) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL4096529 | 0.85 | TRPM8 (0.41) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL16460198 | 0.83 | NNMT (0.40) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL30851652 | 0.81 | PIK3CA (0.37) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL847606 | 0.81 | EGFR (0.43) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL781008 | 0.75 | NAPRT (0.56) | MLYCDTRPM8RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13265171 | 0.73 | MLYCD (0.40) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL21679329 | 0.73 | MLYCD (0.43) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL13265167 | 0.73 | MLYCD (0.40) | MLYCDTRPM8PIK3CAMTORCLK1 | |
| SCHEMBL27782317 | 0.73 | NAPRT (0.47) | SMN1; SMN2SORT1GABRA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |