Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.37 |
| ▸ | MTOR | P42345 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16460198 | 0.83 | NNMT (0.40) | PIK3CAMTORALDH1A1KDM4EHPGD | |
| SCHEMBL3834955 | 0.83 | TUBB4A (0.41) | PIK3CAMTORALDH1A1KDM4EHPGD | |
| SCHEMBL847606 | 0.81 | EGFR (0.43) | PIK3CAMTORALDH1A1CLK1DYRK1A | |
| SCHEMBL20116582 | 0.81 | MLYCD (0.38) | PIK3CAMTORKDM4ECLK1DYRK1A | |
| SCHEMBL1266209 | 0.76 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTGLA | |
| SCHEMBL29942878 | 0.76 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTGLA | |
| SCHEMBL14917429 | 0.73 | PARP1 (0.53) | ALDH1A1KDM4EHPGDMAPTNNMT | |
| SCHEMBL18840131 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHPGDIKBKBLIMK1 | |
| SCHEMBL167457 | 0.73 | GABRP (0.55) | ALDH1A1KDM4EMAPTGABRPGABRD | |
| SCHEMBL11969585 | 0.73 | GRM5 (0.36) | PIK3CAMTORALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |