Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 14/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116098 | 0.81 | SSTR5 (0.41) | SSTR5 | |
| SCHEMBL20676639 | 0.69 | MAPT (0.37) | — | |
| SCHEMBL20116708 | 0.67 | KIT (0.37) | — | |
| SCHEMBL20116804 | 0.64 | MAPT (0.34) | — | |
| SCHEMBL20117183 | 0.64 | MAPT (0.40) | — | |
| SCHEMBL29426821 | 0.64 | HDAC8 (0.36) | — | |
| SCHEMBL20116438 | 0.63 | TSHR (0.43) | — | |
| SCHEMBL20116749 | 0.63 | NR1H4 (0.45) | KCNH2 | |
| SCHEMBL19373594 | 0.61 | KMO (0.40) | — | |
| SCHEMBL30410846 | 0.61 | CHEK1 (0.41) | KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |