Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 17/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116798 | 0.85 | KIT (0.42) | KIT | |
| SCHEMBL20117197 | 0.82 | KIT (0.38) | KITGRM5 | |
| SCHEMBL20116758 | 0.82 | LDHA (0.40) | KITCPT1A | |
| SCHEMBL20676636 | 0.82 | LMNA (0.46) | GRM5 | |
| SCHEMBL20676473 | 0.81 | KIT (0.36) | KITCPT1ATBK1GRM5 | |
| SCHEMBL20117272 | 0.80 | KIT (0.36) | KITCPT1AGRM5 | |
| SCHEMBL20116726 | 0.78 | KIT (0.43) | KIT | |
| SCHEMBL20116857 | 0.78 | HTT (0.42) | KIT | |
| SCHEMBL20676700 | 0.77 | KIT (0.39) | KITCPT1AGRM5 | |
| SCHEMBL20116695 | 0.76 | GRM5 (0.35) | KITGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |