Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 12/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676473 | 0.83 | KIT (0.36) | KITGRM5SMN1; SMN2LMNATSHR | |
| SCHEMBL20116888 | 0.82 | KIT (0.39) | KITGRM5 | |
| SCHEMBL20116758 | 0.82 | LDHA (0.40) | KITSMN1; SMN2LMNATSHR | |
| SCHEMBL20117272 | 0.81 | KIT (0.36) | KITGRM5SMN1; SMN2LMNATSHR | |
| SCHEMBL20116449 | 0.79 | GRM5 (0.37) | KITGRM5SMN1; SMN2LMNATSHR | |
| SCHEMBL20676700 | 0.78 | KIT (0.39) | KITGRM5SMO | |
| SCHEMBL20117204 | 0.77 | TBK1 (0.38) | KITSMN1; SMN2LMNASMO | |
| SCHEMBL20676503 | 0.76 | S1PR1 (0.34) | KIT | |
| SCHEMBL20116836 | 0.74 | SMN1; SMN2 (0.43) | KITSMN1; SMN2LMNATSHRSMO | |
| SCHEMBL20676713 | 0.74 | FAAH (0.40) | KITGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |