Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 14/20 | 0.36 |
| ▸ | GRM5 | P41594 | 5/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676529 | 0.91 | SMO (0.39) | KITNR1H4 | |
| SCHEMBL20116879 | 0.82 | MAPT (0.36) | — | |
| SCHEMBL20676712 | 0.82 | GRM5 (0.40) | GRM5 | |
| SCHEMBL20116751 | 0.81 | LMNA (0.53) | NR1H4 | |
| SCHEMBL20676713 | 0.80 | FAAH (0.40) | KITGRM5 | |
| SCHEMBL20117300 | 0.80 | FAAH (0.39) | KITGRM5 | |
| SCHEMBL20676467 | 0.79 | SMO (0.43) | KITNR1H4 | |
| SCHEMBL20116823 | 0.78 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL20116745 | 0.77 | HSD11B1 (0.51) | GRM5 | |
| SCHEMBL20116723 | 0.77 | LMNA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |