SCHEMBL20117577

SCHEMBL20117577

CCOc1cc(F)c2c(c1)-c1ccc(C)c(F)c1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.36
FFAR1 O14842 3/20 0.35
PPARD Q03181 1/20 0.35
NQO1 P15559 1/20 0.34
KAT6A Q92794 3/20 0.33
FFAR4 Q5NUL3 1/20 0.33
HMOX1 P09601 2/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102387 0.81 CTSL (0.37) PTGS2FFAR1NQO1FFAR4MAPT
SCHEMBL20111320 0.80 PTGS1 (0.35) PTGS2MAPTL3MBTL1MEN1KMT2A
SCHEMBL20111294 0.75 CAMKK1 (0.35) PTGS2FFAR4ALDH1A1
SCHEMBL16852406 0.75 HMOX1 (0.43) PTGS2FFAR1PPARDNQO1FFAR4
SCHEMBL20102386 0.73 CAMKK1 (0.34) FFAR1MEN1KMT2ACYP2C9
SCHEMBL14220258 0.71 NQO1 (0.52) FFAR1PPARDNQO1FFAR4MAPT
SCHEMBL15710186 0.70 NQO1 (0.48) PTGS2FFAR1NQO1MAPTL3MBTL1
SCHEMBL10388263 0.69 NQO1 (0.54) PTGS2FFAR1NQO1FFAR4HMOX1
SCHEMBL20102616 0.69 TDP2 (0.31) PTGS2LMNAHPGD
SCHEMBL20102414 0.69 FGFR2 (0.39) PTGS2MAPTL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315583-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-05-02 EP disclosed