Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17879751 | 0.83 | HSD17B10 (0.38) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL18810693 | 0.80 | HSD17B10 (0.37) | HSD17B10ALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL18810692 | 0.77 | HSD17B10 (0.40) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL17883522 | 0.75 | ALDH1A1 (0.48) | HSD17B10ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL18810700 | 0.75 | HSD17B10 (0.38) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL17883523 | 0.72 | ALDH1A1 (0.47) | HSD17B10ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL17879764 | 0.70 | HSD17B10 (0.38) | HSD17B10ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL4243158 | 0.68 | HSD17B10 (0.55) | HSD17B10ALDH1A1LMNAESR1ESR2 | |
| SCHEMBL9419143 | 0.68 | ALOX15 (0.35) | HSD17B10ALDH1A1LMNAESR1ESR2 | |
| SCHEMBL8574752 | 0.67 | HSD17B10 (0.46) | HSD17B10ALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118968-A1 | TOPCOAT COMPOSITIONS CONTAINING FLUORINATED THERMAL ACID GENERATORS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-05-03 | — | — | US | disclosed |