Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157299 | 0.86 | POLB (0.62) | ALDH1A1ESR1ESR2POLBSERPINE1 | |
| SCHEMBL29599097 | 0.86 | POLB (0.62) | ALDH1A1ESR1ESR2POLBSERPINE1 | |
| SCHEMBL4901587 | 0.86 | POLB (0.62) | ALDH1A1ESR1ESR2POLBSERPINE1 | |
| SCHEMBL19196134 | 0.85 | AMY1A (0.47) | HSD17B10ALDH1A1HPGDKDM4EESR1 | |
| SCHEMBL1577726 | 0.84 | ESR1 (0.48) | ESR1ESR2POLBSERPINE1BACE1 | |
| SCHEMBL29567634 | 0.84 | ALDH1A1 (0.47) | HSD17B10ALDH1A1HPGDKDM4EESR1 | |
| SCHEMBL27584947 | 0.82 | ESR1 (0.47) | ESR1ESR2POLBSERPINE1BACE1 | |
| SCHEMBL28297127 | 0.82 | GABRA1 (0.56) | HSD17B10ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL12486810 | 0.81 | RPS6KA3 (0.56) | HSD17B10ALDH1A1POLBCA2 | |
| SCHEMBL12486812 | 0.81 | RPS6KA3 (0.56) | HSD17B10ALDH1A1POLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835623-B2 | Manganese-based chelate conjugates for molecular MR imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190001003-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | THE GENERAL HOSPITAL CORPORATION | 2019-01-03 | — | — | US | disclosed |
| US-20180118968-A1 | TOPCOAT COMPOSITIONS CONTAINING FLUORINATED THERMAL ACID GENERATORS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-05-03 | — | — | US | disclosed |
| US-20090082590-A1 | 4-Mercaptophenyl ester of acetic acid and process for producing the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| CN-101175721-A | Acetic acid (4-mercaptophenyl) ester and method for producing same | SUMITOMO SEIKA CHEMICALS (JP) | 2008-05-07 | — | — | CN | disclosed |
| EP-1882683-A1 | 4-MERCAPTOPHENYL ESTER OF ACETIC ACID AND PROCESS FOR PRODUCING THE SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2008-01-30 | — | — | EP | disclosed |
| EP-0714785-B1 | Sulfonated phenol (salt) containing color-developing agents and color-developing sheets | MITSUI CHEMICALS INC (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5647896-A | MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0714785-A1 | Sulfonated phenol (salt) containing color-developing agents and color-developing sheets | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0283898-A2 | Preparation process of aryldiazidsulfonic acids | HOECHST CELANESE CORPORATION (US) | 1988-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190001003-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | MPI, MAG, MNS1 | HSD17B10 4727/4885ALDH1A1 4356/4885HPGD 3202/4885 |
| US-20090082590-A1 | 4-Mercaptophenyl ester of acetic acid and process for producing the same | MPST, ACMSD, ACACA | HSD17B10 156/4885ALDH1A1 17/4885HPGD 1535/4885 |
| US-10835623-B2 | Manganese-based chelate conjugates for molecular MR imaging | MPI, MAG, MNS1 | HSD17B10 4727/4885ALDH1A1 4356/4885HPGD 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.