SCHEMBL8574752

SCHEMBL8574752

NCC(=O)OCc1cc(S(=O)(=O)O)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
CA2 P00918 8/20 0.35
CA1 P00915 7/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
NSD2 O96028 1/20 0.34
DUSP3 P51452 1/20 0.34
PTPN5 P54829 1/20 0.34
CASP6 P55212 1/20 0.34
PTPN11 Q06124 1/20 0.34
KMT2A Q03164 1/20 0.34
NT5E P21589 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28806134 0.76 ALDH1A1 (0.49) HSD17B10ALDH1A1KDM4EHPGDLMNA
SCHEMBL8575483 0.76 CA1 (0.46) ALDH1A1KDM4EPOLBCA2CA1
SCHEMBL9855769 0.73 IDO1 (0.55) ALDH1A1CA2
SCHEMBL4243158 0.72 HSD17B10 (0.55) HSD17B10ALDH1A1KDM4EHPGDLMNA
SCHEMBL8631508 0.71 XDH (0.49) ALDH1A1KDM4EHPGDPOLBKMT2A
SCHEMBL30066779 0.71 HSD17B10 (0.54) HSD17B10ALDH1A1KDM4EHPGDLMNA
SCHEMBL6908078 0.71 HSD17B10 (0.54) HSD17B10ALDH1A1KDM4EHPGDLMNA
SCHEMBL8594875 0.69 KAT8 (0.56) HSD17B10ALDH1A1KDM4ELMNACYP1A2
Ethylene SCHEMBL17060539 0.68 HSD17B10 (0.50) HSD17B10ALDH1A1KDM4EHPGDLMNA
SCHEMBL57630 0.68 LMNA (0.62) ALDH1A1LMNACA2CA1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998053893-A1 EXTRACTION AGENTS AND METHOD FOR USE THEREOF HAMPSHIRE CHEMICAL AB (SE) 1998-12-03 WO claimed
WO-1998017857-A1 REMOVAL OF METALS FROM TREATMENT FLUIDS IN A CELLULOSE PULP MILL HAMPSHIRE CHEMICAL AB (SE) 1998-04-30 WO claimed
EP-0225051-B1 THE TREATMENT OF AQUEOUS SYSTEMS W.R. Grace & Co.-Conn. (US) 1992-02-19 EP claimed
US-4721532-A Removal of iron fouling in cooling water systems W. R. GRACE & CO. (US) 1988-01-26 US claimed
WO-1998053893-A1 EXTRACTION AGENTS AND METHOD FOR USE THEREOF HAMPSHIRE CHEMICAL AB (SE) 1998-12-03 WO disclosed
WO-1998017857-A1 REMOVAL OF METALS FROM TREATMENT FLUIDS IN A CELLULOSE PULP MILL HAMPSHIRE CHEMICAL AB (SE) 1998-04-30 WO disclosed