Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335207 | 0.85 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL12349893 | 0.85 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL12464357 | 0.82 | KCNH2 (0.41) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL17938305 | 0.81 | KCNH2 (0.38) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL28832445 | 0.80 | TRPV4 (0.44) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL12425101 | 0.80 | KCNH2 (0.37) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL17938310 | 0.79 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL16622003 | 0.79 | KCNH2 (0.36) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL20117900 | 0.79 | P2RX7 (0.35) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL20130672 | 0.79 | P2RX7 (0.35) | KCNH2MAP4K4PIK3CAMINK1PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116224-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116224-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, CHIA, ALPG | KCNH2 2831/4885MAP4K4 3585/4885PIK3CA 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.