Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.44 |
| ▸ | BACE1 | P56817 | 9/20 | 0.44 |
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118058 | 1.00 | ACHE (0.44) | ACHEBACE1BCHEOPRM1OPRL1 | |
| SCHEMBL20118053 | 0.79 | MGLL (0.41) | KMT2AMEN1 | |
| SCHEMBL20118229 | 0.79 | MGLL (0.41) | KMT2AMEN1 | |
| SCHEMBL20118127 | 0.79 | MGLL (0.41) | KMT2AMEN1 | |
| SCHEMBL13879568 | 0.77 | MGLL (0.47) | KMT2ARAB9A | |
| SCHEMBL21151261 | 0.74 | ADRB1 (0.47) | KMT2AMEN1 | |
| SCHEMBL20118120 | 0.74 | MGLL (0.45) | KMT2AMEN1 | |
| SCHEMBL20118398 | 0.74 | MKNK1 (0.43) | OPRM1KMT2AMEN1 | |
| SCHEMBL20118126 | 0.74 | MKNK1 (0.43) | OPRM1KMT2AMEN1 | |
| SCHEMBL20118393 | 0.71 | GAA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |