Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118127 | 1.00 | MGLL (0.41) | MGLLPGRHSD11B1ALOX5POLB | |
| SCHEMBL20118053 | 0.86 | MGLL (0.41) | MGLLPGRHSD11B1ALOX5POLB | |
| SCHEMBL13879568 | 0.84 | MGLL (0.47) | MGLLPGRALOX5POLBKMT2A | |
| SCHEMBL20118120 | 0.81 | MGLL (0.45) | MGLLPGRHSD11B1ALOX5POLB | |
| SCHEMBL21151261 | 0.81 | ADRB1 (0.47) | MGLLPGRALOX5POLBMEN1 | |
| SCHEMBL20118398 | 0.81 | MKNK1 (0.43) | MGLLPGRMEN1KMT2AALDH1A1 | |
| SCHEMBL20118126 | 0.81 | MKNK1 (0.43) | MGLLPGRMEN1KMT2AALDH1A1 | |
| SCHEMBL20118058 | 0.79 | ACHE (0.44) | MEN1KMT2A | |
| SCHEMBL20118059 | 0.79 | ACHE (0.44) | MEN1KMT2A | |
| SCHEMBL20118393 | 0.78 | GAA (0.43) | MGLLPGRALOX5POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |