Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CCNC | P24863 | 3/20 | 0.32 |
| ▸ | CDK8 | P49336 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118162 | 0.83 | KMT2A (0.40) | ADRA1DADRA1AADRA1BL3MBTL1MKNK1 | |
| SCHEMBL20118057 | 0.82 | BCL2A1 (0.34) | BCL2A1 | |
| SCHEMBL20118239 | 0.82 | BCL2A1 (0.34) | BCL2A1 | |
| SCHEMBL20118234 | 0.79 | BCL2A1 (0.37) | MKNK1MKNK2BCL2A1LMNACCNC | |
| SCHEMBL18208163 | 0.72 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BL3MBTL1MKNK1 | |
| SCHEMBL20118395 | 0.71 | KMT2A (0.39) | ADRA1DADRA1AADRA1BL3MBTL1MKNK1 | |
| SCHEMBL20118233 | 0.69 | KDM4E (0.49) | KDM4E | |
| SCHEMBL20118216 | 0.66 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1TDP1GAAKDM4E | |
| SCHEMBL19132697 | 0.66 | RORC (0.47) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL20118108 | 0.64 | PSEN1 (0.35) | ALDH1A1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |