Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118453 | 0.79 | RAB9A (0.47) | ALDH1A1MAPK1MAPTKMT2AKDM4E | |
| SCHEMBL20118486 | 0.77 | CYP19A1 (0.40) | ALDH1A1CYP19A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL24763942 | 0.76 | F2 (0.35) | ADRB2ADRB1ADRB3ALDH1A1F2 | |
| SCHEMBL24763828 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP19A1MAPTMEN1KMT2A | |
| SCHEMBL20118645 | 0.75 | CYP19A1 (0.42) | CYP19A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20118551 | 0.73 | MAN2B1 (0.36) | ALDH1A1MAPK1PKMHSD17B10 | |
| SCHEMBL20118279 | 0.73 | L3MBTL1 (0.45) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL12199548 | 0.69 | RAB9A (0.57) | ADRB2ADRB1ADRB3ALDH1A1MAPK1 | |
| SCHEMBL20118281 | 0.69 | F2 (0.71) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL24763936 | 0.68 | RAB9A (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081513-A1 | PRODRUGS OF KALLIKREIN INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |