Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057486 | 0.77 | SLC6A2 (0.46) | ALDH1A1MAPTDRD2DRD4KCNH2 | |
| SCHEMBL5547589 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTDPP8DPP9DPP7 | |
| SCHEMBL7168073 | 0.76 | LMNA (0.40) | ALDH1A1MAPTKCNH2HSD17B10CYP3A4 | |
| SCHEMBL23482191 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPTHDAC1HDAC6AADAT | |
| SCHEMBL13212460 | 0.72 | MAPT (0.39) | ALDH1A1MAPTKCNH2HSD17B10CYP1A2 | |
| SCHEMBL13212464 | 0.72 | MAPT (0.39) | ALDH1A1MAPT | |
| SCHEMBL10311212 | 0.70 | NOTUM (0.46) | ALDH1A1MAPTDPP8DPP9DPP7 | |
| SCHEMBL10092850 | 0.68 | ALDH1A1 (0.46) | ALDH1A1HDAC1HDAC6DRD2DRD4 | |
| SCHEMBL12031043 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MAPTHDAC1HDAC6DRD2 | |
| SCHEMBL10311209 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTSRD5A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |