Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495301 | 0.77 | SLC6A1 (0.42) | TP53DRD3KCNH2ALDH1A1 | |
| SCHEMBL20118737 | 0.76 | ALDH1A1 (0.41) | MAPTKMT2AMEN1TSHRKCNH2 | |
| Hydrochloric Acid SCHEMBL7163639 | 0.76 | SLC6A1 (0.41) | TP53DRD3KCNH2ALDH1A1 | |
| SCHEMBL7168069 | 0.74 | MTNR1A (0.46) | LMNAPOLBTP53MAPTKMT2A | |
| SCHEMBL7167706 | 0.74 | ALDH1A1 (0.48) | LMNAMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL6963720 | 0.72 | HTR2A (0.53) | LMNATP53MAPTKMT2AMEN1 | |
| SCHEMBL13057486 | 0.71 | SLC6A2 (0.46) | LMNAPOLBMAPTKMT2AMEN1 | |
| SCHEMBL13485712 | 0.70 | SLC6A2 (0.44) | LMNAPOLBTP53MAPTKMT2A | |
| SCHEMBL13456561 | 0.70 | ALDH1A1 (0.42) | LMNAPOLBTP53MAPTKMT2A | |
| SCHEMBL25784150 | 0.67 | KDM4E (0.66) | POLBMAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |