Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 3/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329882 | 0.86 | CCR1 (0.54) | MMP14PRMT5LMNACCR1CCR8 | |
| SCHEMBL15322937 | 0.82 | LMNA (0.50) | MMP14PRMT5LMNACCR1CCR8 | |
| SCHEMBL31178765 | 0.79 | PRMT5 (0.47) | MMP14PRMT5LMNACCR1CCR8 | |
| SCHEMBL8103326 | 0.79 | HSP90AA1 (0.59) | MMP14PRMT5LMNACCR1CCR8 | |
| SCHEMBL27318336 | 0.77 | HSP90AA1 (0.57) | MMP14PRMT5LMNACCR1CCR8 | |
| SCHEMBL12066579 | 0.77 | PRMT5 (0.45) | MMP14PRMT5LMNACCR1CCR8 | |
| SCHEMBL9029872 | 0.77 | PRMT5 (0.45) | PRMT5LMNACCR1CCR8L3MBTL1 | |
| SCHEMBL11470588 | 0.77 | ALDH1A1 (0.62) | MMP14LMNACCR1CCR8L3MBTL1 | |
| SCHEMBL21130135 | 0.75 | L3MBTL1 (0.58) | MMP14LMNACCR1CCR8L3MBTL1 | |
| SCHEMBL22250697 | 0.75 | HSP90AA1 (0.59) | MMP14LMNACCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976337-B1 | 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LTD (IN) | 2018-05-02 | — | — | EP | disclosed |