Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.71 |
| ▸ | CA1 | P00915 | 9/20 | 0.71 |
| ▸ | CA9 | Q16790 | 9/20 | 0.71 |
| ▸ | CA12 | O43570 | 7/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957622 | 0.93 | CA2 (0.76) | CA2CA1CA9CA12POLB | |
| SCHEMBL3187957 | 0.83 | CA2 (1.00) | CA2CA1CA9CA12POLB | |
| SCHEMBL3201396 | 0.78 | POLB (0.65) | CA2CA1CA9CA12POLB | |
| SCHEMBL3201402 | 0.78 | POLB (0.65) | CA2CA1CA9CA12POLB | |
| SCHEMBL9923580 | 0.77 | CA1 (0.63) | CA2CA1CA9CA12POLB | |
| SCHEMBL20111164 | 0.76 | MAPT (0.44) | CA2CA1CA9CA12POLB | |
| SCHEMBL3267784 | 0.75 | ALOX15 (0.66) | POLBALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL3179732 | 0.75 | KMT2A (0.67) | POLBALDH1A1MT-CO2ALOX5SMN1; SMN2 | |
| SCHEMBL13265283 | 0.75 | LMNA (0.59) | POLBALDH1A1MAPTGAAHPGD | |
| SCHEMBL5645885 | 0.75 | ALDH1A1 (0.58) | CA2CA1CA9CA12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118857-A1 | PROCESS FOR FUNCTIONALISING POLYMERS | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-05-03 | — | — | US | disclosed |