Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060599 | 0.95 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL1421887 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL30069060 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL27883374 | 0.83 | MAPT (0.57) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL8891437 | 0.79 | IRAK4 (0.38) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL10740410 | 0.77 | LMNA (0.56) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5144939 | 0.77 | HTT (0.51) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL335038 | 0.77 | MAPT (0.73) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL29405531 | 0.77 | MAPT (0.73) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL4880989 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |