Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120180 | 0.82 | HSD17B10 (0.42) | MAPTNPC1RAB9AHSD17B10CNR1 | |
| SCHEMBL18029295 | 0.81 | PTGS2 (0.43) | MAPTNPC1RAB9ACNR1CNR2 | |
| SCHEMBL20119984 | 0.78 | NPC1 (0.41) | MAPTNPC1RAB9AHSD17B10MEN1 | |
| SCHEMBL21392209 | 0.78 | EGFR (0.49) | NPC1RAB9AEGFRHDAC6ALDH1A1 | |
| SCHEMBL19872770 | 0.78 | EGFR (0.48) | MAPTNPC1RAB9AEGFRHDAC6 | |
| SCHEMBL20119872 | 0.77 | EGFR (0.46) | MAPTNPC1RAB9AHSD17B10EGFR | |
| SCHEMBL18509698 | 0.75 | EGFR (0.46) | NPC1RAB9AEGFRHDAC6ALDH1A1 | |
| SCHEMBL21392207 | 0.75 | EGFR (0.46) | NPC1RAB9AEGFRSMN1; SMN2HDAC6 | |
| SCHEMBL18509710 | 0.75 | EGFR (0.46) | NPC1RAB9AEGFRHDAC6ALDH1A1 | |
| SCHEMBL20120013 | 0.75 | EGFR (0.46) | NPC1RAB9AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |