Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120059 | 0.82 | MAPT (0.41) | HSD17B10MAPTNPC1RAB9AEGFR | |
| SCHEMBL18029387 | 0.81 | PTGS2 (0.43) | HSD17B10MAPTNPC1RAB9AALOX15 | |
| SCHEMBL20935249 | 0.78 | MAPT (0.41) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23226320 | 0.78 | PIK3CD (0.35) | HSD17B10MAPTNPC1RAB9AALOX15 | |
| SCHEMBL20120037 | 0.77 | GPR17 (0.41) | HSD17B10MAPTALOX15SMN1; SMN2CYP2C19 | |
| SCHEMBL18509489 | 0.77 | CTSB (0.43) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19872661 | 0.76 | PLA2G2A (0.47) | MAPTNPC1RAB9AEGFRALDH1A1 | |
| SCHEMBL21395993 | 0.75 | GPR17 (0.48) | NPC1RAB9AEGFRCNR1CNR2 | |
| SCHEMBL21392131 | 0.75 | GPR17 (0.48) | NPC1RAB9AEGFRALDH1A1 | |
| SCHEMBL18509302 | 0.75 | EGFR (0.46) | NPC1RAB9AEGFRSMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |