Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817643 | 0.75 | TDP1 (0.45) | TDP1ACHEGPR35ALDH1A1HSD17B10 | |
| SCHEMBL9287738 | 0.75 | TDP1 (0.41) | TDP1PARP1GPR35ALDH1A1HSD17B10 | |
| SCHEMBL13833540 | 0.71 | PARP1 (0.47) | PARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8980518 | 0.70 | PARP1 (0.43) | PARP1 | |
| SCHEMBL5073994 | 0.69 | LMNA (0.36) | TDP1ACHEGPR35ALDH1A1HSD17B10 | |
| SCHEMBL28393356 | 0.69 | TDP1 (0.39) | TDP1ACHEGPR35ALDH1A1HSD17B10 | |
| SCHEMBL5274188 | 0.68 | PNMT (0.51) | TDP1ACHEGPR35ALDH1A1HSD17B10 | |
| SCHEMBL376449 | 0.68 | ALDH1A1 (0.46) | TDP1ACHEGPR35ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11734144 | 0.68 | TDP1 (0.41) | TDP1ACHEGPR35ALDH1A1HSD17B10 | |
| SCHEMBL31386914 | 0.68 | PARP1 (0.41) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315486-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | Tosoh Corporation (JP) | 2018-05-02 | — | — | EP | disclosed |