Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780027 | 0.85 | KIF11 (0.48) | MAPK1ALDH1A1TAAR1ESR1ESR2 | |
| SCHEMBL2341327 | 0.81 | ESR1 (0.41) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL3264960 | 0.78 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL3708602 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL842144 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL6055442 | 0.75 | CYP2C19 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Bromide SCHEMBL8601711 | 0.74 | MAPK1 (0.48) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL34188 | 0.74 | ALDH1A1 (0.40) | MAPK1ALDH1A1TSHR | |
| SCHEMBL29624141 | 0.74 | ALDH1A1 (0.40) | MAPK1ALDH1A1TSHR | |
| Tert-Butylbenzene SCHEMBL28274873 | 0.74 | MAPK1 (0.48) | MAPK1ALDH1A1TAAR1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265240-B2 | With CO in the presence of a source of hydroxyl groups (water or an alcohol) and a catalyst obtained by combining a Group VIII metal or a compound thereof and a bidentate phosphine, e.g., tri(dibenzylideneacetone)di-palladium | LUCITE INTERNATIONAL UK LIMITED (GB) | 2007-09-04 | — | — | US | claimed |
| CN-1140532-C | Process for preparation of bisphosphines | 卢西特国际英国有限公司 | 2004-03-03 | — | — | CN | claimed |
| CN-1293675-A | Process for preparation of bisphosphines | INIOS ACRYLIC ACID BRITISH PLC (GB) | 2001-05-02 | — | — | CN | claimed |
| CN-115772195-A | Pyridine-based phosphine ligand compound and application thereof | 惠州凯特立斯科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-110312701-A | Process for preparing unsaturated carboxylic acids by carbonylation of allyl alcohol and acylates thereof | 巴斯夫欧洲公司 | 2019-10-08 | — | — | CN | disclosed |
| US-20190248815-A1 | ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
| EP-3480204-A1 | ORGANIC MAGNESIUM PHOSPHIDE AND METHOD FOR PRODUCING SAME, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ORGANIC PHOSPHORUS-CONTAINING COMPOUND USING SAID PHOSPHIDE | Hokko Chemical Industry Co., Ltd. (JP) | 2019-05-08 | — | — | EP | disclosed |
| CN-109476680-A | The manufacturing method of organic magnesium phosphide and manufacturing method, its complex compound and manufacturing method and the organic phosphorus compound using the phosphide | 北兴化学工业株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-107980011-A | The method of homogeneous catalysis reduction amination carbonyls | 巴斯夫欧洲公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-107629093-A | Double (phosphino-) ferrocene ligands of 1,1` for alkoxycarbonylation | 赢创德固赛有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107628952-A | Method for making alkene alkoxycarbonylation in the medium with low Bronsted acid concentration | 赢创德固赛有限公司 | 2018-01-26 | — | — | CN | disclosed |
| WO-2006084891-A1 | PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2006-08-17 | — | — | WO | disclosed |
| CN-1816513-A | Process for the hydroformylation of olefinically unsaturated compounds | LUCITE INT UK LTD (GB) | 2006-08-09 | — | — | CN | disclosed |
| CN-1795164-A | Process for the carbonylation of a conjugated diene | SHELL INT RESEARCH (NL) | 2006-06-28 | — | — | CN | disclosed |
| CN-1795159-A | Method for hydrocarboxylation of ethylenically unsaturated carboxylic acids | SHELL INT RESEARCH (NL) | 2006-06-28 | — | — | CN | disclosed |
| EP-1625109-A1 | PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004103948-A1 | PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2004-12-02 | — | — | WO | disclosed |
| CN-1073546-C | Process for carbonylation of ethylene and catalyst system for use thereof | INIOS ACRYLIC ACID BRITISH PLC (GB) | 2001-10-24 | — | — | CN | disclosed |
| CN-1276779-A | Production of esters | INIOS ACRYLIC G B LTD (GB) | 2000-12-13 | — | — | CN | disclosed |
| CN-1171098-A | Process for the carbonylation of ethylene and catalyst system for use therein | ICI PLC (GB) | 1998-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248815-A1 | ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE | IPMK, PPIP5K2, PIP4K2C | MAPK1 1764/4885ALDH1A1 4699/4885TAAR1 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.