Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.43 |
| ▸ | LPL | P06858 | 6/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734240 | 0.75 | LIPG (0.50) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL21383623 | 0.74 | LIPG (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17734224 | 0.74 | LIPG (0.49) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL23582308 | 0.73 | F11 (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2012044 | 0.73 | DGAT1 (0.48) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL21383621 | 0.73 | LIPG (0.54) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27380258 | 0.72 | LIPG (0.47) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16256313 | 0.72 | LIPG (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1982315 | 0.71 | DGAT1 (0.47) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL24776579 | 0.71 | LPL (0.56) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334636-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010032147-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2010-03-25 | — | — | WO | disclosed |