Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012118 | 1.00 | L3MBTL3 (0.31) | L3MBTL3L3MBTL1HTR6 | |
| SCHEMBL2012120 | 1.00 | L3MBTL3 (0.31) | L3MBTL3L3MBTL1HTR6 | |
| Hydrochloric Acid SCHEMBL29716176 | 0.99 | L3MBTL3 (0.30) | L3MBTL3L3MBTL1HTR6 | |
| SCHEMBL2009518 | 0.77 | HTR6 (0.38) | L3MBTL3L3MBTL1HTR6 | |
| Hydrochloric Acid SCHEMBL3696745 | 0.76 | HTR6 (0.37) | L3MBTL3L3MBTL1HTR6 | |
| SCHEMBL577679 | 0.74 | HTR6 (0.31) | HTR6 | |
| SCHEMBL577677 | 0.74 | HTR6 (0.31) | HTR6 | |
| SCHEMBL4400728 | 0.70 | KDM4E (0.39) | L3MBTL1 | |
| SCHEMBL4178230 | 0.69 | — | — | |
| SCHEMBL2151647 | 0.68 | HTR6 (0.39) | L3MBTL3L3MBTL1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340029-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2011-07-06 | — | — | EP | claimed |
| WO-2010030359-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARJMACEUTICALS, INC. (US) | 2010-03-18 | — | — | WO | claimed |
| EP-2504344-A1 | HEPATITIS C INHIBITOR COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011063502-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-03 | — | — | WO | disclosed |