Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577679 | 1.00 | HTR6 (0.31) | HTR6 | |
| SCHEMBL2012122 | 0.74 | L3MBTL3 (0.31) | HTR6 | |
| SCHEMBL2012120 | 0.74 | L3MBTL3 (0.31) | HTR6 | |
| SCHEMBL2012118 | 0.74 | L3MBTL3 (0.31) | HTR6 | |
| Hydrochloric Acid SCHEMBL29716176 | 0.73 | L3MBTL3 (0.30) | HTR6 | |
| SCHEMBL4400728 | 0.72 | KDM4E (0.39) | — | |
| SCHEMBL6844970 | 0.63 | CTSB (0.46) | — | |
| SCHEMBL13071410 | 0.62 | ALOX15 (0.37) | — | |
| SCHEMBL4178230 | 0.60 | — | — | |
| SCHEMBL7621022 | 0.60 | HTR6 (0.38) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417134-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |