Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444448 | 0.82 | MTNR1A (0.51) | HPGDALDH1A1PKMTDP1CA12 | |
| SCHEMBL13696441 | 0.78 | POLB (0.46) | HPGDALDH1A1TDP1CA12CA1 | |
| SCHEMBL9112879 | 0.75 | CA1 (0.46) | HPGDALDH1A1PKMTDP1CA12 | |
| SCHEMBL146841 | 0.73 | CA1 (0.61) | HPGDALDH1A1PKMTDP1CA12 | |
| SCHEMBL5481572 | 0.73 | ALDH1A1 (0.46) | HPGDALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL15211345 | 0.73 | HSD17B10 (0.44) | HPGDALDH1A1PKMCA12CA1 | |
| SCHEMBL31604178 | 0.72 | TRPA1 (0.46) | HPGDALDH1A1TDP1CA12CA1 | |
| SCHEMBL17384531 | 0.72 | ALDH1A1 (0.38) | HPGDALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL8088430 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTLMNANOS3 | |
| SCHEMBL2863659 | 0.72 | CA12 (0.43) | HPGDALDH1A1TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963456-B2 | Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD (JP) | 2018-05-08 | — | — | US | disclosed |
| US-9963456-B2 | Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD (JP) | 2018-05-08 | — | — | US | disclosed |