SCHEMBL146841

SCHEMBL146841

COc1cccc(OC)c1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA7 P43166 3/20 0.61
CA9 Q16790 3/20 0.61
CA12 O43570 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA4 P22748 1/20 0.61
MAPT P10636 5/20 0.52
ALDH1A1 P00352 4/20 0.52
MAPK1 P28482 3/20 0.52
TP53 P04637 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
LMNA P02545 2/20 0.52
ALOX15 P16050 2/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX12 P18054 1/20 0.52
HSD17B10 Q99714 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5624415 0.89 CA1 (0.50) CA1CA2CA7CA9CA12
Boric Acid SCHEMBL5237071 0.89 ENPP2 (0.54) CA1CA2CA7CA9CA12
SCHEMBL9046346 0.87 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL7921177 0.86 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL78554 0.86 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL29352478 0.86 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL28575044 0.86 CA1 (0.52) CA1CA2CA7CA9CA12
Fluoride SCHEMBL27638422 0.84 MAPT (0.50) CA1CA2CA7CA9CA12
SCHEMBL13263181 0.83 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL12728608 0.83 MAPT (0.48) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-9293711-B2 Organic semiconductor formulations POLYERA CORPORATION (US) 2016-03-22 US claimed
WO-2007069986-A1 NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS ASTRAZENECA AB (SE) 2007-06-21 WO claimed
US-20050124614-A1 3,4-Dihydroisoquinolin-1-one derivatives as inducers of apoptosis AXYS PHARMACEUTICALS, INC. (US) 2005-06-09 US claimed
WO-2004004727-A1 3,4-DIHYDROISOQUINOLIN-1-ONE DERIVATIVES AS INDUCERS OF APOPTOSIS AXYS PHARMACEUTICALS, INC. (US) 2004-01-15 WO claimed
US-5028574-A Coordination catalysts for producing high molecular weight addition polymers, less drag in pipelines CONOCO INC. (US) 1991-07-02 US claimed
CN-119980266-A Method for electrochemical catalysis of direct amination reaction of aromatic alkane hydrocarbon bond 南京工业大学 2025-05-13 CN disclosed
WO-2025078808-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LIMITED (GB) 2025-04-17 WO disclosed
US-20250122212-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LIMITED (GB) 2025-04-17 US disclosed
CN-119776157-A Application of Penicillium poland in improving flavor of black tea product through fermentation 湖南农业大学 2025-04-08 CN disclosed
US-20250034110-A1 LPAR1 ANTAGONISTS AND USES THEREOF Pipeline Therapeutics, Inc. 2025-01-30 US disclosed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 US disclosed
US-20240390446-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING INFLAMMATORY DISEASES INCLUDING DIABETES AND THYROID DISEASES ALKALAY RACHEL (IL) 2024-11-28 US disclosed
EP-0108156-A1 Improved method for the preparation of non-crystalline polymers of high molecular weight Conoco Phillips Company (US) 1984-05-16 EP disclosed
US-4358572-A POLYMERIZATION OF ALPH-OLEFINS USING A CATALYTIC SLURRY OF TITANIUM HALIDE, HYDROCARBON DILUENT, ETHER, AND ALUMINUM COMPOUND CONOCO INC. (US) 1982-11-09 US disclosed
EP-0002666-B1 1,2-BENZISOXAZOLYLOXY (OR THIO) ACETIC ACIDS AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-17 EP disclosed
US-4272634-A Process for the production of intermediate oxidation products of toluenes having ether linkages DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1981-06-09 US disclosed
US-4246176-A Synthesis of 5-aroyl-1-hydrocarbylpyrrole-2-acetic acid ETHYL CORPORATION (US) 1981-01-20 US disclosed
US-4220605-A LIQUID PHASE USING A SOLVENT OF LOW LOWER CARBOXYLIC ACID OR ANHYDRIDE, A SOLUBLE COBALT SALT AND BROMINE OR A BROMINE COMPOUND DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1980-09-02 US disclosed
EP-0002666-A1 1,2-Benzisoxazolyloxy (or thio) acetic acids and related compounds, process for their preparation and medicines containing them HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 CA1 44/4885CA2 93/4885CA7 72/4885
US-20050124614-A1 3,4-Dihydroisoquinolin-1-one derivatives as inducers of apoptosis CASP3, BAX, BAD CA1 2987/4885CA2 3217/4885CA7 3809/4885
US-20250034110-A1 LPAR1 ANTAGONISTS AND USES THEREOF LPAR1, LPAR2, LPAR3 CA1 4618/4885CA2 4108/4885CA7 4310/4885
US-20240390446-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING INFLAMMATORY DISEASES INCLUDING DIABETES AND THYROID DISEASES TPO, TNF, ADAMTS13 CA1 1785/4885CA2 2697/4885CA7 1814/4885
US-20250122212-A1 NOVEL COMPOUNDS CYP11B1, CYP11B2, UGT1A1 CA1 1755/4885CA2 3686/4885CA7 1230/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR CA1 140/4885CA2 458/4885CA7 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.