Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 5/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286749 | 0.88 | CTSB (0.39) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL19719340 | 0.87 | MEN1 (0.34) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL23348903 | 0.81 | — | — | |
| SCHEMBL21849676 | 0.81 | TPSAB1 (0.39) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL19286750 | 0.79 | CTSB (0.37) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL23191634 | 0.79 | MEN1 (0.32) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL31275685 | 0.77 | CTSB (0.42) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL24040106 | 0.77 | CTSB (0.40) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL19884607 | 0.77 | TPSAB1 (0.41) | MEN1KMT2ALMNACTSBCTSK | |
| SCHEMBL25790651 | 0.76 | CTSB (0.46) | MEN1KMT2ALMNACTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962454-B2 | Antibody drug conjugates (ADC) that bind to 191P4D12 proteins | AGENSYS, INC. (US) | 2018-05-08 | — | — | US | disclosed |