Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19884607 | 0.90 | TPSAB1 (0.41) | TPSAB1PRSS1ABCB1PLGCTSL | |
| SCHEMBL19286749 | 0.86 | CTSB (0.39) | TPSAB1PRSS1ABCB1PLGCTSL | |
| SCHEMBL20121890 | 0.81 | MEN1 (0.37) | TPSAB1PRSS1ABCB1PLGCTSL | |
| SCHEMBL25790651 | 0.79 | CTSB (0.46) | ABCB1CTSLCTSBCTSSCTSK | |
| SCHEMBL19389590 | 0.78 | PRSS1 (0.43) | TPSAB1PRSS1ABCB1APPKDM4E | |
| SCHEMBL24336897 | 0.77 | MEN1 (0.47) | TPSAB1PRSS1PLGKDM4EALDH1A1 | |
| SCHEMBL19719340 | 0.77 | MEN1 (0.34) | ABCB1CTSLCTSBCTSSCTSK | |
| SCHEMBL27344037 | 0.76 | APP (0.44) | TPSAB1PRSS1ABCB1APPKDM4E | |
| SCHEMBL19267132 | 0.75 | PRSS1 (0.41) | TPSAB1PRSS1ABCB1CTSLCTSB | |
| SCHEMBL20799986 | 0.75 | TPSAB1 (0.39) | TPSAB1PRSS1ABCB1PLGCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632462-A1 | DIMERIC PROTEIN WITH TRIPLE MUTATIONS | Genmab B.V. (NL) | 2020-04-08 | — | — | EP | disclosed |