Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.31 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699144 | 0.82 | HRH3 (0.33) | L3MBTL3MBTD1L3MBTL1FYN | |
| SCHEMBL23977741 | 0.82 | MEN1 (0.39) | — | |
| SCHEMBL19836467 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL13860756 | 0.79 | L3MBTL3 (0.33) | L3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL20655373 | 0.78 | L3MBTL3 (0.46) | L3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL24185494 | 0.78 | HRH3 (0.32) | L3MBTL3MBTD1L3MBTL1FYN | |
| SCHEMBL23822993 | 0.77 | SIGMAR1 (0.33) | L3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL19699824 | 0.75 | HRH3 (0.33) | L3MBTL3MBTD1 | |
| SCHEMBL19966106 | 0.73 | FDPS (0.35) | — | |
| SCHEMBL19966103 | 0.73 | FDPS (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962382-B2 | Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors | ARRIEN PHARMACEUTICALS LLC (US) | 2018-05-08 | — | — | US | disclosed |