SCHEMBL2012278

SCHEMBL2012278

O=c1cc(Nc2ccccc2)c1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
MAPT P10636 8/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
TDP1 Q9NUW8 5/20 0.52
KDM4E B2RXH2 5/20 0.52
MAPK1 P28482 4/20 0.52
HPGD P15428 3/20 0.52
GLA P06280 2/20 0.52
LMNA P02545 2/20 0.52
CYP3A4 P08684 2/20 0.52
RGS12 O14924 1/20 0.52
GMNN O75496 1/20 0.52
PRKD3 O94806 1/20 0.52
EGFR P00533 1/20 0.52
PRKCG P05129 1/20 0.52
PRKCB P05771 1/20 0.52
SRC P12931 1/20 0.52
PRKCA P17252 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30620470 0.78 NPC1 (0.58) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL30671653 0.78 AKR1C3 (0.41) MAPTMEN1KMT2ALMNAL3MBTL1
SCHEMBL29377177 0.78 MAPT (0.55) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL4541413 0.78 RAD52 (0.42) MAPK1CYP3A4PRKCGPRKCZPRKCD
SCHEMBL30671648 0.78 NPSR1 (0.55) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL30671656 0.78 FADS1 (0.53) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL29376295 0.77 KIF11 (0.49) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL5085669 0.76 NPC1 (0.73) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL30115035 0.75 AKR1C3 (0.47) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL5080930 0.75 HSD17B10 (0.65) ALDH1A1MAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114026077-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2022-02-08 CN claimed
CN-112300172-B Bruton tyrosine kinase inhibitors 比奥根MA公司 2024-01-16 CN disclosed
EP-3953340-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI Industries Ltd. (IN) 2022-02-16 EP disclosed
CN-114026077-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2022-02-08 CN disclosed
WO-2017093698-A1 BIPHOTONIC PHOTOSENSITIZING DENDRIMERS, MANUFACTURING METHOD AND USES UNIVERSITE DE RENNES 1 (FR) 2017-06-08 WO disclosed
EP-2513083-B1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CENTRE NAT RECH SCIENT (FR) 2016-04-06 EP disclosed
US-8709747-B2 Biphotonic photosensitizers, nanoparticles containing the same and their use as drugs CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-04-29 US disclosed
US-20130065849-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-14 US disclosed
EP-2513083-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CNRS Centre National De La Recherche Scientifique (FR) 2012-10-24 EP disclosed
WO-2011073054-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065849-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CCNB1, ABCB1, CA6 ALDH1A1 1670/4885MAPT 1263/4885MEN1 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.