Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20014568 | 0.84 | NOTUM (0.39) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL20123586 | 0.82 | MEN1 (0.33) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL20123720 | 0.76 | NOTUM (0.37) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL20123554 | 0.74 | HSD17B3 (0.43) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL12997790 | 0.72 | SLC6A2 (0.32) | — | |
| SCHEMBL6907006 | 0.70 | CA1 (0.44) | CA1CA2CA4CA6 | |
| SCHEMBL20015254 | 0.70 | NOTUM (0.37) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL20014486 | 0.69 | HSD17B3 (0.50) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL20123579 | 0.69 | HSD17B3 (0.47) | HSD17B3CA1CA2CA4CA6 | |
| SCHEMBL20014809 | 0.69 | ADRA2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |