Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616673 | 0.82 | KDM4E (0.72) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL29795690 | 0.77 | KDM4E (0.66) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL4739612 | 0.77 | KDM4E (0.55) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL5820160 | 0.74 | KDM4E (0.52) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL2301745 | 0.74 | KDM4E (0.77) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL2016630 | 0.74 | KDM4E (0.55) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL2929292 | 0.74 | KDM4E (0.55) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL17294334 | 0.73 | KDM4E (0.64) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL14465322 | 0.73 | HSD17B10 (0.44) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL10254012 | 0.71 | KDM4E (0.62) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |