Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341290 | 0.79 | HTR2C (0.49) | HTR2CDRD1HTR2A | |
| SCHEMBL8746509 | 0.78 | HTR2A (0.52) | HTR2CHTR2ARETHTR2BPDPK1 | |
| SCHEMBL12998159 | 0.76 | ALDH1A1 (0.43) | HTR2CDRD1GAATAS1R3TAS1R1 | |
| SCHEMBL13198466 | 0.72 | HTR2C (0.62) | HTR2CTAS1R3TAS1R1TAS1R2HTR2A | |
| SCHEMBL15577042 | 0.72 | HTR2C (0.62) | HTR2CTAS1R3TAS1R1TAS1R2HTR2A | |
| SCHEMBL12429503 | 0.72 | GPR3 (0.38) | HTR2CGAAHTR2AHTR2B | |
| SCHEMBL10446460 | 0.71 | SLC6A2 (0.36) | HTR2CDRD1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL948086 | 0.69 | ACP3 (0.46) | HTR2CHTR2ARETHTR2BPDPK1 | |
| SCHEMBL14555196 | 0.69 | HTR2A (0.52) | HTR2CHTR2ARETHTR2BPDPK1 | |
| SCHEMBL16385863 | 0.69 | DRD1 (0.64) | HTR2CDRD1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |