Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 3/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784497 | 0.82 | ALDH1A1 (0.36) | BRD4ACLYALDH1A1KDM4ECTSA | |
| SCHEMBL2012467 | 0.81 | SCD (0.45) | SCDKDM4ESMN1; SMN2 | |
| SCHEMBL2008273 | 0.74 | L3MBTL1 (0.49) | BRD4METAP2ACLYSCDALDH1A1 | |
| SCHEMBL12631173 | 0.70 | SCD (0.45) | SCDKDM4ESMN1; SMN2 | |
| SCHEMBL2013556 | 0.68 | KDM4E (0.46) | METAP2SCDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL12631554 | 0.67 | MAPT (0.42) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL12631561 | 0.66 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL12631176 | 0.64 | KDM4E (0.46) | BRD4SCDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2009099 | 0.64 | NFE2L2 (0.42) | SCDALDH1A1SMN1; SMN2 | |
| SCHEMBL783874 | 0.63 | TLR7 (0.42) | SCDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |