Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009099 | 0.89 | NFE2L2 (0.42) | NFE2L2ALDH1A1ADAMTS5P2RY1SLC22A12 | |
| SCHEMBL2484934 | 0.85 | TLR7 (0.42) | TLR7NFE2L2ADAMTS5TRPM8EGLN2 | |
| SCHEMBL2012467 | 0.83 | SCD (0.45) | NFE2L2P2RY1SLC22A12NOTUMSCD | |
| SCHEMBL12631173 | 0.82 | SCD (0.45) | NFE2L2P2RY1SLC22A12SCDSMN1; SMN2 | |
| SCHEMBL12631176 | 0.80 | KDM4E (0.46) | NFE2L2ALDH1A1P2RY1SCDSMN1; SMN2 | |
| SCHEMBL783872 | 0.79 | RXRA (0.44) | NFE2L2ALDH1A1 | |
| SCHEMBL2008455 | 0.77 | GAA (0.41) | NFE2L2ALDH1A1TRPM8 | |
| SCHEMBL12631556 | 0.76 | SCD (0.36) | NFE2L2ADAMTS5P2RY1SLC22A12SCD | |
| SCHEMBL8917002 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CNR2SMN1; SMN2MAPK1 | |
| SCHEMBL784497 | 0.75 | ALDH1A1 (0.36) | TLR7ALDH1A1EGLN2FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071322-A1 | Substituted Pyridopyrazines with a Herbicidal Action | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| EP-2379503-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20110251063-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2011-10-13 | — | — | US | disclosed |
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| WO-2010139658-A1 | SUBSTITUTED PYRIDOPYRAZINES WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010069802-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071322-A1 | Substituted Pyridopyrazines with a Herbicidal Action | PLPBP, PNPO, PFAS | TLR7 4215/4885NFE2L2 1583/4885ALDH1A1 313/4885 |
| US-20110251063-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | DDT, KHK, HK1 | TLR7 4678/4885NFE2L2 1466/4885ALDH1A1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.